Effects of ascorbic acid deficiency on adrenal mitochondrial hydroxylations in guinea pigs.

The effect of ascorbic acid deficiency on adrenal hydroxylation of cholesterol and deoxycorticosterone in guinea pigs was studied by using mitochondria and isolated cytochrome P-450 fractions. The effects obtained were compared with the effects of long-term treatment with ACTH. Advanced scurvy as we...

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Bibliographic Details
Main Authors: I Björkhem, A Kallner, K E Karlmar
Format: Article
Language:English
Published: Elsevier 1978-08-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520412696