Platelet hyperaggregability in high-fat fed rats: A role for intraplatelet reactive-oxygen species production

Platelet hyperaggregability in high-fat fed rats: A role for intraplatelet reactive-oxygen species production

<p>Abstract</p> <p>Background</p> <p>Adiposity greatly increases the risk of atherothrombotic events, a pathological condition where a chronic state of oxidative stress is reported to play a major role. This study aimed to investigate the involvement of (NO)-soluble gua...

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Bibliographic Details
Main Authors: Monteiro Priscila F, Morganti Rafael P, Delbin Maria A, Calixto Marina C, Lopes-Pires Maria E, Marcondes Sisi, Zanesco Angelina, Antunes Edson
Format: Article
Language:English
Published: BMC 2012-01-01
Series:Cardiovascular Diabetology
Subjects:
Platelet aggregation
Obesity
Reactive-oxygen species
Nitric oxide
Cyclic GMP
BAY 41-2272
Online Access:http://www.cardiab.com/content/11/1/5

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