PM2.5 disrupts thyroid hormone homeostasis through activation of the hypothalamic-pituitary-thyroid (HPT) axis and induction of hepatic transthyretin in female rats 2.5

PM2.5 disrupts thyroid hormone homeostasis through activation of the hypothalamic-pituitary-thyroid (HPT) axis and induction of hepatic transthyretin in female rats 2.5

Fine particulate matter (PM2.5), a ubiquitous environmental pollutant, has been indicated to affect thyroid hormone (TH) homeostasis in women, but the detailed mechanism behind this effect remains unclear. The objective of this study was to evaluate the roles of the hypothalamic-pituitary-thyroid (H...

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Bibliographic Details
Main Authors: Xinwen Dong, Weidong Wu, Sanqiao Yao, Haibin Li, Zhichun Li, Li Zhang, Jing Jiang, Jie Xu, Fengquan Zhang
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Ecotoxicology and Environmental Safety
Subjects:
PM2.5
Thyroid hormone
HPT axis
Receptor
Hepatic transthyretin
Biosynthesis
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651320315578

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