Generation of Thyroid Tissues From Embryonic Stem Cells via Blastocyst Complementation In Vivo

Generation of Thyroid Tissues From Embryonic Stem Cells via Blastocyst Complementation In Vivo

The generation of mature, functional, thyroid follicular cells from pluripotent stem cells would potentially provide a therapeutic benefit for patients with hypothyroidism, but in vitro differentiation remains difficult. We earlier reported the in vivo generation of lung organs via blastocyst comple...

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Bibliographic Details
Main Authors: Qingsong Ran, Qiliang Zhou, Kanako Oda, Akihiro Yasue, Manabu Abe, Xulu Ye, Yingchun Li, Toshikuni Sasaoka, Kenji Sakimura, Yoichi Ajioka, Yasuo Saijo
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Endocrinology
Subjects:
blastocyst complementation
embryonic stem cells
Fgf10
pluripotent stem cells
thyroid generation
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2020.609697/full

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