The ERK MAPK Pathway Is Essential for Skeletal Development and Homeostasis

The ERK MAPK Pathway Is Essential for Skeletal Development and Homeostasis

Mitogen-activated protein kinases (MAPKs) are a family of protein kinases that function as key signal transducers of a wide spectrum of extracellular stimuli, including growth factors and pro-inflammatory cytokines. Dysregulation of the extracellular signal-regulated kinase (ERK) MAPK pathway is ass...

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Bibliographic Details
Main Authors: Jung-Min Kim, Yeon-Suk Yang, Kwang Hwan Park, Hwanhee Oh, Matthew B. Greenblatt, Jae-Hyuck Shim
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:International Journal of Molecular Sciences
Subjects:
MAPK
MEK1
MEK2
ERK
osteoblast
osteopenia
cleidocranial dysplasia
Online Access:https://www.mdpi.com/1422-0067/20/8/1803

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