MicroRNA-221/222 Mediates ADSC-Exosome-Induced Cardioprotection Against Ischemia/Reperfusion by Targeting PUMA and ETS-1
Cardiovascular disease is a major health problem in industrialized and developing countries and is the leading cause of death and disability. Myocardial ischemia/reperfusion (I/R) causes cardiomyocyte damage such as apoptosis and hypertrophy. The purpose of this study was to investigate the effects...
Main Authors: | Tsai-Chun Lai, Tzu-Lin Lee, Yu-Chun Chang, Yu-Chen Chen, Shu-Rung Lin, Shu-Wha Lin, Chi-Ming Pu, Jaw-Shiun Tsai, Yuh-Lien Chen |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2020-12-01
|
Series: | Frontiers in Cell and Developmental Biology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fcell.2020.569150/full |
Similar Items
-
Oncogenic role of miRNA-221/222 in breast cancer
by: I Wayan Ardyan Sudharta Putra, et al.
Published: (2018-05-01) -
Biodegradable and biocompatible cationic polymer delivering microRNA-221/222 promotes nerve regeneration after sciatic nerve crush
by: Song J, et al.
Published: (2017-06-01) -
Expression of miR-221/222 is affected by Triclosan in MCF-7 cells
by: Keivan Mobini, et al.
Published: (2019-09-01) -
Influence of miR-221/222 on cardiomyocyte calcium handling and function
by: Maria Knyrim, et al.
Published: (2021-08-01) -
The correlation between microRNA-221/222 cluster overexpression and malignancy: an updated meta-analysis including 2693 patients
by: Zhang P, et al.
Published: (2018-09-01)