Conotoxins Targeting Nicotinic Acetylcholine Receptors: An Overview

Conotoxins Targeting Nicotinic Acetylcholine Receptors: An Overview

Marine snails of the genus Conus are a large family of predatory gastropods with an unparalleled molecular diversity of pharmacologically active compounds in their venom. Cone snail venom comprises of a rich and diverse cocktail of peptide toxins which act on a wide variety of ion channels such as v...

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Bibliographic Details
Main Authors: Eline K. M. Lebbe, Steve Peigneur, Isuru Wijesekara, Jan Tytgat
Format: Article
Language:English
Published: MDPI AG 2014-05-01
Series:Marine Drugs
Subjects:
nicotinic acetylcholine receptor
cone snail toxins
α-conotoxins
mode of action
working mechanism
acetylcholine binding protein
crystallography
docking model
Online Access:http://www.mdpi.com/1660-3397/12/5/2970

Internet

http://www.mdpi.com/1660-3397/12/5/2970

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