Characterizing Sphingosine Kinases and Sphingosine 1-Phosphate Receptors in the Mammalian Eye and Retina

Characterizing Sphingosine Kinases and Sphingosine 1-Phosphate Receptors in the Mammalian Eye and Retina

Sphingosine 1-phosphate (S1P) signaling regulates numerous biological processes including neurogenesis, inflammation and neovascularization. However, little is known about the role of S1P signaling in the eye. In this study, we characterize two sphingosine kinases (SPHK1 and SPHK2), which phosphoryl...

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Bibliographic Details
Main Authors:	Hunter Porter, Hui Qi, Nicole Prabhu, Richard Grambergs, Joel McRae, Blake Hopiavuori, Nawajes Mandal
Format:	Article
Language:	English
Published:	MDPI AG 2018-12-01
Series:	International Journal of Molecular Sciences
Subjects:	S1P sphingosine 1-phosphate S1PR1 sphingosine 1-phosphate receptor 1 S1PR2 S1PR3 sphingosine kinase 1 SPHK2 retina eye
Online Access:	https://www.mdpi.com/1422-0067/19/12/3885

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