Restricted TcR β chain CDR3 clonotype is associated with resolved acute hepatitis B subjects

Restricted TcR β chain CDR3 clonotype is associated with resolved acute hepatitis B subjects

Abstract Background T cells play an important role in the prognosis of hepatitis B virus (HBV) infection, and are involved in the seroconversion of a patient from HBsAb negative to positive. To compare the T-cell receptor β-chain variable region (TcRBV) complementarity-determining region 3 (CDR3) in...

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Bibliographic Details
Main Authors: Dangsheng Xiao, Ju Wang, Zhitao Chen, Xiuyuan Jin, Yirui Xie, Dong Yan, Jiezuan Yang
Format: Article
Language:English
Published: BMC 2021-01-01
Series:BMC Infectious Diseases
Subjects:
T cell receptor
Complementarity-determining region 3
Resolved acute hepatitis B
HBsAg seroconversion
High throughput sequencing
Online Access:https://doi.org/10.1186/s12879-021-05816-2

Internet

https://doi.org/10.1186/s12879-021-05816-2

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