Mechanism of Growth Inhibition of Prostate Cancer Xenografts by Valproic Acid

Mechanism of Growth Inhibition of Prostate Cancer Xenografts by Valproic Acid

Valproic Acid (VPA), a histone deacetylase inhibitor, has been demonstrated to cause a marked decrease in proliferation of prostate cancer (PCa) cells in vitro and a significant reduction in tumor volume in vivo. The goal of this study is to better understand the VPA-induced growth inhibition in viv...

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Bibliographic Details
Main Authors:	Abhinav Sidana, Muwen Wang, Shabana Shabbeer, Wasim H. Chowdhury, George Netto, Shawn E. Lupold, Michael Carducci, Ronald Rodriguez
Format:	Article
Language:	English
Published:	Hindawi Limited 2012-01-01
Series:	Journal of Biomedicine and Biotechnology
Online Access:	http://dx.doi.org/10.1155/2012/180363

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