A systems medicine approach for finding target proteins affecting treatment outcomes in patients with non-Hodgkin lymphoma.

Autoantibody profiling with a systems medicine approach can help identify critical dysregulated signaling pathways (SPs) in cancers. In this way, immunoglobulins G (IgG) purified from the serum samples of 92 healthy controls, 10 pre-treated (PR) non-Hodgkin lymphoma (NHL) patients, and 20 NHL patien...

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Main Authors: Faezeh Ajorloo, Mohammad Vaezi, Alireza Saadat, Seyed Reza Safaee, Behrouz Gharib, Mostafa Ghanei, Seyed Davar Siadat, Farzam Vaziri, Abolfazl Fateh, Mehrdad Pazhouhandeh, Behrouz Vaziri, Reza Moazemi, Fereidoun Mahboudi, Fatemeh Rahimi Jamnani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5593188?pdf=render