Desaturation and heme elevation during COVID-19 infection: A potential prognostic factor of heme oxygenase-1

Increased heme levels, anemia, and desaturation occur during infection. We aimed to compare the levels of heme, heme oxygenase-1 (HO-1), ferritin, and bilirubin in coronavirus disease 2019 (COVID-19) patients at different saturation levels. Heme and HO-1 enzyme levels significantly increased in the...

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Main Authors: Wen-Lin Su, Chih-Pei Lin, Hui-Ching Hang, Ping-Sheng Wu, Ching-Feng Cheng, You-Chen Chao
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:Journal of Microbiology, Immunology and Infection
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1684118220302462
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spelling doaj-3e2aea2051dc4c52b37a3444ca130beb2021-02-21T04:31:59ZengElsevierJournal of Microbiology, Immunology and Infection1684-11822021-02-01541113116Desaturation and heme elevation during COVID-19 infection: A potential prognostic factor of heme oxygenase-1Wen-Lin Su0Chih-Pei Lin1Hui-Ching Hang2Ping-Sheng Wu3Ching-Feng Cheng4You-Chen Chao5Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City, Taiwan; School of Medicine, Tzu Chi University, Hualien, TaiwanSchool of Medicine, Tzu Chi University, Hualien, Taiwan; Department of Pathology and Laboratory Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei, TaiwanDepartment of Pathology and Laboratory Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei, TaiwanSchool of Medicine, Tzu Chi University, Hualien, Taiwan; Department of Pediatrics, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei, TaiwanSchool of Medicine, Tzu Chi University, Hualien, Taiwan; Department of Pediatrics, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei, TaiwanSchool of Medicine, Tzu Chi University, Hualien, Taiwan; Department of Internal Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City, Taiwan; Corresponding author. Department of Internal Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, 289 Jianguo Rd, Xindian Dist., New Taipei City 23142, Taiwan, ROC. Fax: +886 2 66289009.Increased heme levels, anemia, and desaturation occur during infection. We aimed to compare the levels of heme, heme oxygenase-1 (HO-1), ferritin, and bilirubin in coronavirus disease 2019 (COVID-19) patients at different saturation levels. Heme and HO-1 enzyme levels significantly increased in the low SpO2 group, but further studies are required.http://www.sciencedirect.com/science/article/pii/S1684118220302462COVID-19HemeHeme oxygenase-1SARS-CoV-2
collection DOAJ
language English
format Article
sources DOAJ
author Wen-Lin Su
Chih-Pei Lin
Hui-Ching Hang
Ping-Sheng Wu
Ching-Feng Cheng
You-Chen Chao
spellingShingle Wen-Lin Su
Chih-Pei Lin
Hui-Ching Hang
Ping-Sheng Wu
Ching-Feng Cheng
You-Chen Chao
Desaturation and heme elevation during COVID-19 infection: A potential prognostic factor of heme oxygenase-1
Journal of Microbiology, Immunology and Infection
COVID-19
Heme
Heme oxygenase-1
SARS-CoV-2
author_facet Wen-Lin Su
Chih-Pei Lin
Hui-Ching Hang
Ping-Sheng Wu
Ching-Feng Cheng
You-Chen Chao
author_sort Wen-Lin Su
title Desaturation and heme elevation during COVID-19 infection: A potential prognostic factor of heme oxygenase-1
title_short Desaturation and heme elevation during COVID-19 infection: A potential prognostic factor of heme oxygenase-1
title_full Desaturation and heme elevation during COVID-19 infection: A potential prognostic factor of heme oxygenase-1
title_fullStr Desaturation and heme elevation during COVID-19 infection: A potential prognostic factor of heme oxygenase-1
title_full_unstemmed Desaturation and heme elevation during COVID-19 infection: A potential prognostic factor of heme oxygenase-1
title_sort desaturation and heme elevation during covid-19 infection: a potential prognostic factor of heme oxygenase-1
publisher Elsevier
series Journal of Microbiology, Immunology and Infection
issn 1684-1182
publishDate 2021-02-01
description Increased heme levels, anemia, and desaturation occur during infection. We aimed to compare the levels of heme, heme oxygenase-1 (HO-1), ferritin, and bilirubin in coronavirus disease 2019 (COVID-19) patients at different saturation levels. Heme and HO-1 enzyme levels significantly increased in the low SpO2 group, but further studies are required.
topic COVID-19
Heme
Heme oxygenase-1
SARS-CoV-2
url http://www.sciencedirect.com/science/article/pii/S1684118220302462
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