Identification of Heat Shock Protein 60 as a Regulator of Neutral Sphingomyelinase 2 and Its Role in Dopamine Uptake.

Identification of Heat Shock Protein 60 as a Regulator of Neutral Sphingomyelinase 2 and Its Role in Dopamine Uptake.

Activation of sphingomyelinase (SMase) by extracellular stimuli is the major pathway for cellular production of ceramide, a bioactive lipid mediator acting through sphingomyelin (SM) hydrolysis. Previously, we reported the existence of six forms of neutral pH-optimum and Mg(2+)-dependent SMase (N-SM...

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Main Authors: Kyong-Hoon Ahn, Seok-Kyun Kim, Jong-Min Choi, Sung-Yun Jung, Jong-Hoon Won, Moon-Jung Back, Zhicheng Fu, Ji-Min Jang, Hae-Chan Ha, Dae-Kyong Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3686747?pdf=render

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http://europepmc.org/articles/PMC3686747?pdf=render

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