2.2 Modest Region-Specific, Sex-Independent Aortic Remodelling when Hypertension is Superimposed on Aging
Background: Aging and hypertension often co-occur, which complicates distinguishing their biomechanical effects on arteries clinically. While aortic elastin (half-life ~70 years) is reduced in human aging, in mouse aging (lifespan ~2 years) it remains mostly intact. Knock-out of elastin-associated g...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Atlantis Press
2020-02-01
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Series: | Artery Research |
Online Access: | https://www.atlantis-press.com/article/125934391/view |