Treatment of native valve endocarditis due to coagulase negative staphylococci, complicated by a drug reaction with eosinophilia and systemic symptoms (DRESS syndrome)

• Main Authors: S. H. C. K. De Silva, K. Jayatilleka, S. Subasinghe, D. Ariyawanse, C. De Silva
• Format: Article
• Language: English
• Published: Sri Lankan Society for Microbiology 2017-05-01
• Series: Sri Lankan Journal of Infectious Diseases
• Subjects: native valve endocarditis, coagulase negative staphylococcus, linezolid, dress syndrome, cerebral emboli
• Online Access: https://sljid.sljol.info/articles/8121
• ISSN: 2012-8169; 2448-9654

<p>Coagulase negative staphylococci (CoNS) are a rare cause of native valve endocarditis (NVE). However, they are emerging as important pathogens of NVE.  We  describe  a  61  year  old  male  who  developed  NVE  caused by CoNS and presented  with  cerebral  embolic  phenomena.  He was treated with vancomycin and subsequently with linezolid. He developed a drug reaction with eosinophilia and systemic symptoms (DRESS syndrome) to linezolid which was managed successfully.  The patient’s recovery was good after six weeks of treatment with anti-staphylococcal antibiotics.</p>