Volume Transmission and Pain Perception

Volume Transmission and Pain Perception

Volume transmission (VT) is the diffusion through the brain extracellular fluid of neurotransmitters released at points that may be remote from the target cells with the resulting activation of extrasynaptic receptors. VT appears to play multiple roles in the brain in normal and abnormal activity, b...

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Main Authors: Gilberto C. Castañeda-Hernàndez, Paul Bach-y-Rita
Format: Article
Language:English
Published: Hindawi Limited 2003-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/tsw.2003.53
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spelling doaj-3dcc8446e80543c38c0f3bda5af3db702020-11-25T01:33:28ZengHindawi LimitedThe Scientific World Journal1537-744X2003-01-01367768310.1100/tsw.2003.53Volume Transmission and Pain PerceptionGilberto C. Castañeda-Hernàndez0Paul Bach-y-Rita1Centro de Investigación y Estudios Avanzados del Instituto Politécnico Nacional, Avenida Instituto Politécnico Nacional 2508, México, D.F. 07300, MexicoDepartments of Orthopedics and Rehabilitation Medicine, and Biomedical Engineering, University of Wisconsin-Madison, 1300 University Avenue, Madison, Wisconsin, USAVolume transmission (VT) is the diffusion through the brain extracellular fluid of neurotransmitters released at points that may be remote from the target cells with the resulting activation of extrasynaptic receptors. VT appears to play multiple roles in the brain in normal and abnormal activity, brain plasticity and drug actions. The relevance of VT to pain perception has been explored in this review.http://dx.doi.org/10.1100/tsw.2003.53
collection DOAJ
language English
format Article
sources DOAJ
author Gilberto C. Castañeda-Hernàndez
Paul Bach-y-Rita
spellingShingle Gilberto C. Castañeda-Hernàndez
Paul Bach-y-Rita
Volume Transmission and Pain Perception
The Scientific World Journal
author_facet Gilberto C. Castañeda-Hernàndez
Paul Bach-y-Rita
author_sort Gilberto C. Castañeda-Hernàndez
title Volume Transmission and Pain Perception
title_short Volume Transmission and Pain Perception
title_full Volume Transmission and Pain Perception
title_fullStr Volume Transmission and Pain Perception
title_full_unstemmed Volume Transmission and Pain Perception
title_sort volume transmission and pain perception
publisher Hindawi Limited
series The Scientific World Journal
issn 1537-744X
publishDate 2003-01-01
description Volume transmission (VT) is the diffusion through the brain extracellular fluid of neurotransmitters released at points that may be remote from the target cells with the resulting activation of extrasynaptic receptors. VT appears to play multiple roles in the brain in normal and abnormal activity, brain plasticity and drug actions. The relevance of VT to pain perception has been explored in this review.
url http://dx.doi.org/10.1100/tsw.2003.53
work_keys_str_mv AT gilbertoccastanedahernandez volumetransmissionandpainperception
AT paulbachyrita volumetransmissionandpainperception
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