Phloretin as a Potent Natural TLR2/1 Inhibitor Suppresses TLR2-Induced Inflammation

Phloretin as a Potent Natural TLR2/1 Inhibitor Suppresses TLR2-Induced Inflammation

Toll-like receptor 2 (TLR2) responses are involved in various inflammatory immune disorders. Phloretin is a naturally occurring dietary flavonoid that is abundant in fruit. Here, we investigated whether the anti-inflammatory activity of phloretin is mediated through TLR2 pathways, and whether phlore...

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Bibliographic Details
Main Authors: Jieun Kim, Prasannavenkatesh Durai, Dasom Jeon, In Duk Jung, Seung Jun Lee, Yeong-Min Park, Yangmee Kim
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Nutrients
Subjects:
phloretin
dietary flavonoid
inflammation
TLR2
TLR1
inhibitor
Online Access:http://www.mdpi.com/2072-6643/10/7/868

Internet

http://www.mdpi.com/2072-6643/10/7/868

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