Structure-function investigation of vsp serotypes of the spirochete Borrelia hermsii.

BACKGROUND:Relapsing fever (RF) spirochetes are notable for multiphasic antigenic variation of polymorphic outer membrane lipoproteins, a phenomenon responsible for immune evasion. An additional role in tissue localization is suggested by the finding that isogenic serotypes 1 (Bt1) and 2 (Bt2) of th...

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Bibliographic Details
Main Authors: Rohit Mehra, Diana Londoño, Marie Sondey, Catherine Lawson, Diego Cadavid
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2766631?pdf=render