The cellular prion protein: a player in immunological quiescence

The cellular prion protein: a player in immunological quiescence

Despite intensive studies since the 1990s, the physiological role of the cellular prion protein (PrPC) remains elusive. Here, we present a novel concept suggesting that PrPC contributes to immunological quiescence in addition to cell protection. PrPC is highly expressed in diverse organs that by mul...

Full description

Bibliographic Details
Main Authors: Maren Kolltveit Bakkebø, Sophie eMouillet-Richard, Arild Espenes Espenes, Wilfred eGoldmann, Jörg eTatzelt, Michael Andreas Tranulis
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-09-01
Series:Frontiers in Immunology
Subjects:
Cytoprotection
Inflammation
Alzheimer
prion protein
neurodegeneration
Cell signaling
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00450/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00450/full

Similar Items