Light-induced structural changes in a short light, oxygen, voltage (LOV) protein revealed by molecular dynamics simulations – implications for the understanding of LOV photoactivation.

Light-induced structural changes in a short light, oxygen, voltage (LOV) protein revealed by molecular dynamics simulations – implications for the understanding of LOV photoactivation.

The modularity of light, oxygen, voltage (LOV) blue-light photoreceptors has recently been exploited for the design of LOV-based optogenetic tools, which allow the light-dependent control of biological functions. For the understanding of LOV sensory function and hence the optimal design of LOV-based...

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Bibliographic Details
Main Authors: Marco eBocola, Ulrich eSchwaneberg, Karl-Erich eJaeger, Ulrich eKrauss
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-10-01
Series:Frontiers in Molecular Biosciences
Subjects:
signaling
optogenetics
molecular dynamics
photoreceptor
LOV domain
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmolb.2015.00055/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmolb.2015.00055/full

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