CLytA-DAAO, Free and Immobilized in Magnetic Nanoparticles, Induces Cell Death in Human Cancer Cells

CLytA-DAAO, Free and Immobilized in Magnetic Nanoparticles, Induces Cell Death in Human Cancer Cells

D-amino acid oxidase (DAAO) catalyzes the oxidation of D-amino acids generating hydrogen peroxide, a potential producer of reactive oxygen species. In this study, we used a CLytA-DAAO chimera, both free and bound to magnetic nanoparticles, against colon carcinoma, pancreatic adenocarcinoma, and glio...

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Bibliographic Details
Main Authors: María Fuentes-Baile, Daniel Bello-Gil, Elizabeth Pérez-Valenciano, Jesús M. Sanz, Pilar García-Morales, Beatriz Maestro, María P. Ventero, Cristina Alenda, Víctor M. Barberá, Miguel Saceda
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Biomolecules
Subjects:
magnetic nanoparticle
cancer therapy
reactive oxygen species
oxidative damage
cytotoxicity
choline-binding proteins
Online Access:https://www.mdpi.com/2218-273X/10/2/222

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