Development and validation of a quantitative, high-throughput, fluorescent-based bioassay to detect schistosoma viability.

Schistosomiasis, caused by infection with the blood fluke Schistosoma, is responsible for greater than 200,000 human deaths per annum. Objective high-throughput screens for detecting novel anti-schistosomal targets will drive 'genome to drug' lead translational science at an unprecedented...

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Bibliographic Details
Main Authors: Emily Peak, Iain W Chalmers, Karl F Hoffmann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-07-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC2910722?pdf=render