Oral Tori in Chronic Peritoneal Dialysis Patients.

The pathogenesis of oral tori has long been debated and is thought to be the product of both genetic and environmental factors, including occlusal forces. Another proposed mechanism for oral tori is the combination of biomechanical forces, particularly in the oral cavity, combined with cortical bone...

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Main Authors: Chia-Lin Hsu, Ching-Wei Hsu, Pei-Ching Chang, Wen-Hung Huang, Cheng-Hao Weng, Huang-Yu Yang, Shou-Hsuan Liu, Kuan-Hsing Chen, Shu-Man Weng, Chih-Chun Chang, I-Kuan Wang, Aileen I Tsai, Tzung-Hai Yen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4898723?pdf=render
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spelling doaj-3db31a1c278d46c38a335e5ad1d545392020-11-25T00:07:59ZengPublic Library of Science (PLoS)PLoS ONE1932-62032016-01-01116e015698810.1371/journal.pone.0156988Oral Tori in Chronic Peritoneal Dialysis Patients.Chia-Lin HsuChing-Wei HsuPei-Ching ChangWen-Hung HuangCheng-Hao WengHuang-Yu YangShou-Hsuan LiuKuan-Hsing ChenShu-Man WengChih-Chun ChangI-Kuan WangAileen I TsaiTzung-Hai YenThe pathogenesis of oral tori has long been debated and is thought to be the product of both genetic and environmental factors, including occlusal forces. Another proposed mechanism for oral tori is the combination of biomechanical forces, particularly in the oral cavity, combined with cortical bone loss and trabecular expansion, as one might see in the early stages of primary hyperparathyroidism. This study investigated the epidemiology of torus palatinus (TP) and torus mandibularis (TM) in peritoneal dialysis patients, and analyzed the influences of hyperparathyroidism on the formation of oral tori.In total, 134 peritoneal dialysis patients were recruited between July 1 and December 31, 2015 for dental examinations for this study. Patients were categorized into two subgroups based on the presence or absence of oral tori. Demographic, hematological, biochemical, and dialysis-related data were obtained for analysis.The prevalence of oral tori in our sample group was high at 42.5% (57 of 134), and most patients with oral tori were female (61.4%). The most common location of tori was TP (80.7%), followed by TP and TM (14.0%), then TM (5.3%). All 54 TP cases were at the midline, and most were <2 cm (59.3%), flat (53.7%), and located in the premolar region (40.7%). Of the 11 TM cases, all were bilateral and symmetric, mostly <2 cm (81.9%), lobular (45.4%), and located at premolar region (63.6%). Interestingly, patients with oral tori had slightly lower serum levels of intact parathyroid hormones than those without oral tori, but the difference was not statistically significant (317.3±292.0 versus 430.1±492.6 pg/mL, P = 0.126). In addition, patients with oral tori did not differ from patients without tori in inflammatory variables such as serum high sensitivity C-reactive protein levels (6.6±8.2 versus 10.3±20.2 mg/L, P = 0.147) or nutritional variables such as serum albumin levels (3.79±0.38 versus 3.77±0.45 g/dL, P = 0.790). Furthermore, there were no differences between patients with and without oral tori in dialysis adequacy (weekly Kt/Vurea, 2.14±0.39 versus 2.11±0.33, P = 0.533; weekly creatinine clearance rate, 59.31±17.58 versus 58.57±13.20 L/1.73 m2, P = 0.781), or peritoneal membrane transporter characteristics (P = 0.098).Secondary hyperparathyroidism does not contribute to the formation of tori in peritoneal dialysis patients. Further studies are warranted.http://europepmc.org/articles/PMC4898723?pdf=render
collection DOAJ
language English
format Article
sources DOAJ
author Chia-Lin Hsu
Ching-Wei Hsu
Pei-Ching Chang
Wen-Hung Huang
Cheng-Hao Weng
Huang-Yu Yang
Shou-Hsuan Liu
Kuan-Hsing Chen
Shu-Man Weng
Chih-Chun Chang
I-Kuan Wang
Aileen I Tsai
Tzung-Hai Yen
spellingShingle Chia-Lin Hsu
Ching-Wei Hsu
Pei-Ching Chang
Wen-Hung Huang
Cheng-Hao Weng
Huang-Yu Yang
Shou-Hsuan Liu
Kuan-Hsing Chen
Shu-Man Weng
Chih-Chun Chang
I-Kuan Wang
Aileen I Tsai
Tzung-Hai Yen
Oral Tori in Chronic Peritoneal Dialysis Patients.
PLoS ONE
author_facet Chia-Lin Hsu
Ching-Wei Hsu
Pei-Ching Chang
Wen-Hung Huang
Cheng-Hao Weng
Huang-Yu Yang
Shou-Hsuan Liu
Kuan-Hsing Chen
Shu-Man Weng
Chih-Chun Chang
I-Kuan Wang
Aileen I Tsai
Tzung-Hai Yen
author_sort Chia-Lin Hsu
title Oral Tori in Chronic Peritoneal Dialysis Patients.
title_short Oral Tori in Chronic Peritoneal Dialysis Patients.
title_full Oral Tori in Chronic Peritoneal Dialysis Patients.
title_fullStr Oral Tori in Chronic Peritoneal Dialysis Patients.
title_full_unstemmed Oral Tori in Chronic Peritoneal Dialysis Patients.
title_sort oral tori in chronic peritoneal dialysis patients.
publisher Public Library of Science (PLoS)
series PLoS ONE
issn 1932-6203
publishDate 2016-01-01
description The pathogenesis of oral tori has long been debated and is thought to be the product of both genetic and environmental factors, including occlusal forces. Another proposed mechanism for oral tori is the combination of biomechanical forces, particularly in the oral cavity, combined with cortical bone loss and trabecular expansion, as one might see in the early stages of primary hyperparathyroidism. This study investigated the epidemiology of torus palatinus (TP) and torus mandibularis (TM) in peritoneal dialysis patients, and analyzed the influences of hyperparathyroidism on the formation of oral tori.In total, 134 peritoneal dialysis patients were recruited between July 1 and December 31, 2015 for dental examinations for this study. Patients were categorized into two subgroups based on the presence or absence of oral tori. Demographic, hematological, biochemical, and dialysis-related data were obtained for analysis.The prevalence of oral tori in our sample group was high at 42.5% (57 of 134), and most patients with oral tori were female (61.4%). The most common location of tori was TP (80.7%), followed by TP and TM (14.0%), then TM (5.3%). All 54 TP cases were at the midline, and most were <2 cm (59.3%), flat (53.7%), and located in the premolar region (40.7%). Of the 11 TM cases, all were bilateral and symmetric, mostly <2 cm (81.9%), lobular (45.4%), and located at premolar region (63.6%). Interestingly, patients with oral tori had slightly lower serum levels of intact parathyroid hormones than those without oral tori, but the difference was not statistically significant (317.3±292.0 versus 430.1±492.6 pg/mL, P = 0.126). In addition, patients with oral tori did not differ from patients without tori in inflammatory variables such as serum high sensitivity C-reactive protein levels (6.6±8.2 versus 10.3±20.2 mg/L, P = 0.147) or nutritional variables such as serum albumin levels (3.79±0.38 versus 3.77±0.45 g/dL, P = 0.790). Furthermore, there were no differences between patients with and without oral tori in dialysis adequacy (weekly Kt/Vurea, 2.14±0.39 versus 2.11±0.33, P = 0.533; weekly creatinine clearance rate, 59.31±17.58 versus 58.57±13.20 L/1.73 m2, P = 0.781), or peritoneal membrane transporter characteristics (P = 0.098).Secondary hyperparathyroidism does not contribute to the formation of tori in peritoneal dialysis patients. Further studies are warranted.
url http://europepmc.org/articles/PMC4898723?pdf=render
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