Divergent midbrain circuits orchestrate escape and freezing responses to looming stimuli in mice

In response to environmental threats, such as visual looming stimuli, mice either freeze or escape. Here the authors demonstrate that these two behaviors are mediated by separate tectofugal pathways formed by parvalbumin-positive neurons in the superior colliculus.

Bibliographic Details
Main Authors: Congping Shang, Zijun Chen, Aixue Liu, Yang Li, Jiajing Zhang, Baole Qu, Fei Yan, Yaning Zhang, Weixiu Liu, Zhihui Liu, Xiaofei Guo, Dapeng Li, Yi Wang, Peng Cao
Format: Article
Language:English
Published: Nature Publishing Group 2018-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-03580-7
Description
Summary:In response to environmental threats, such as visual looming stimuli, mice either freeze or escape. Here the authors demonstrate that these two behaviors are mediated by separate tectofugal pathways formed by parvalbumin-positive neurons in the superior colliculus.
ISSN:2041-1723