Downregulated miR-195 detected in preeclamptic placenta affects trophoblast cell invasion via modulating ActRIIA expression.

Downregulated miR-195 detected in preeclamptic placenta affects trophoblast cell invasion via modulating ActRIIA expression.

Preeclampsia (PE) is a pregnancy-specific syndrome manifested by on-set of hypertension and proteinuria after 20 weeks of gestation. Abnormal placenta development has been generally accepted as initial cause of the disorder. Recently, miR-195 was found to be down-regulated in preeclamptic placentas...

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Bibliographic Details
Main Authors: Yang Bai, Weiwei Yang, Hui-xia Yang, Qinping Liao, Gang Ye, Guodong Fu, Lei Ji, Peng Xu, Hao Wang, Yu-xia Li, Chun Peng, Yan-ling Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3378540?pdf=render

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