Hepatitis C virus cell-cell transmission and resistance to direct-acting antiviral agents.

Hepatitis C virus cell-cell transmission and resistance to direct-acting antiviral agents.

Hepatitis C virus (HCV) is transmitted between hepatocytes via classical cell entry but also uses direct cell-cell transfer to infect neighboring hepatocytes. Viral cell-cell transmission has been shown to play an important role in viral persistence allowing evasion from neutralizing antibodies. In...

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Bibliographic Details
Main Authors: Fei Xiao, Isabel Fofana, Laura Heydmann, Heidi Barth, Eric Soulier, François Habersetzer, Michel Doffoël, Jens Bukh, Arvind H Patel, Mirjam B Zeisel, Thomas F Baumert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-05-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24830295/pdf/?tool=EBI

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