Latent-space embedding of expression data identifies gene signatures from sputum samples of asthmatic patients
Abstract Background The pathogenesis of asthma is a complex process involving multiple genes and pathways. Identifying biomarkers from asthma datasets, especially those that include heterogeneous subpopulations, is challenging. Potentially, autoencoders provide ideal frameworks for such tasks as the...
Main Authors: | Shaoke Lou, Tianxiao Li, Daniel Spakowicz, Xiting Yan, Geoffrey Lowell Chupp, Mark Gerstein |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-10-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12859-020-03785-y |
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