Making Meaningful Clinical Use of Biomarkers

This review discusses the current state of biomarker discovery for the purposes of diagnostics and therapeutic monitoring. We underscore relevant challenges that have defined the gap between biomarker discovery and meaningful clinical use. We highlight recent advancements in and propose a way to thi...

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Bibliographic Details
Main Authors:	Matthew J Selleck, Maheswari Senthil, Nathan R Wall
Format:	Article
Language:	English
Published:	SAGE Publishing 2017-06-01
Series:	Biomarker Insights
Online Access:	https://doi.org/10.1177/1177271917715236

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spelling	doaj-3d6a242dc7b4459d943ad0d5c0523ed52020-11-25T03:46:06ZengSAGE PublishingBiomarker Insights1177-27192017-06-011210.1177/1177271917715236Making Meaningful Clinical Use of BiomarkersMatthew J Selleck0Maheswari Senthil1Nathan R Wall2Division of Surgical Oncology, Department of Surgery, Loma Linda University Medical Center, Loma Linda, CA, USADivision of Surgical Oncology, Department of Surgery, Loma Linda University Medical Center, Loma Linda, CA, USADivision of Biochemistry, Department of Basic Sciences and Center for Health Disparities & Molecular Medicine, Loma Linda University Medical Center, Loma Linda, CA, USAThis review discusses the current state of biomarker discovery for the purposes of diagnostics and therapeutic monitoring. We underscore relevant challenges that have defined the gap between biomarker discovery and meaningful clinical use. We highlight recent advancements in and propose a way to think about future biomarker development.https://doi.org/10.1177/1177271917715236
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Matthew J Selleck Maheswari Senthil Nathan R Wall
spellingShingle	Matthew J Selleck Maheswari Senthil Nathan R Wall Making Meaningful Clinical Use of Biomarkers Biomarker Insights
author_facet	Matthew J Selleck Maheswari Senthil Nathan R Wall
author_sort	Matthew J Selleck
title	Making Meaningful Clinical Use of Biomarkers
title_short	Making Meaningful Clinical Use of Biomarkers
title_full	Making Meaningful Clinical Use of Biomarkers
title_fullStr	Making Meaningful Clinical Use of Biomarkers
title_full_unstemmed	Making Meaningful Clinical Use of Biomarkers
title_sort	making meaningful clinical use of biomarkers
publisher	SAGE Publishing
series	Biomarker Insights
issn	1177-2719
publishDate	2017-06-01
description	This review discusses the current state of biomarker discovery for the purposes of diagnostics and therapeutic monitoring. We underscore relevant challenges that have defined the gap between biomarker discovery and meaningful clinical use. We highlight recent advancements in and propose a way to think about future biomarker development.
url	https://doi.org/10.1177/1177271917715236
work_keys_str_mv	AT matthewjselleck makingmeaningfulclinicaluseofbiomarkers AT maheswarisenthil makingmeaningfulclinicaluseofbiomarkers AT nathanrwall makingmeaningfulclinicaluseofbiomarkers
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Making Meaningful Clinical Use of Biomarkers

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