Differential expression profiles of long noncoding RNAs and mRNAs in human bone marrow mesenchymal stem cells after exposure to a high dosage of dexamethasone

Differential expression profiles of long noncoding RNAs and mRNAs in human bone marrow mesenchymal stem cells after exposure to a high dosage of dexamethasone

Abstract Background Abnormalities in apoptosis, cell cycle, proliferation, and differentiation of human bone marrow mesenchymal stem cells (hBMSCs) significantly impact bone metabolism and remodeling, resulting in various skeletal disorders. Long-term exposure to a high dosage of dexamethasone (Dex)...

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Bibliographic Details
Main Authors: Tao Li, Yingxing Xu, Yingzhen Wang, Yaping Jiang
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Stem Cell Research & Therapy
Subjects:
MSCs
Gene expression
Long noncoding RNA
Apoptosis
Dexamethasone
Online Access:https://doi.org/10.1186/s13287-020-02040-8

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