Tumor Cellular and Microenvironmental Cues Controlling Invadopodia Formation

Tumor Cellular and Microenvironmental Cues Controlling Invadopodia Formation

During the metastatic progression, invading cells might achieve degradation and subsequent invasion into the extracellular matrix (ECM) and the underlying vasculature using invadopodia, F-actin-based and force-supporting protrusive membrane structures, operating focalized proteolysis. Their formatio...

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Bibliographic Details
Main Authors: Ilenia Masi, Valentina Caprara, Anna Bagnato, Laura Rosanò
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
invadopodia
cytoskeleton
cell invasion
metastasis
extracellular matrix
receptors
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.584181/full

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