Afadin regulates puncta adherentia junction formation and presynaptic differentiation in hippocampal neurons.

Afadin regulates puncta adherentia junction formation and presynaptic differentiation in hippocampal neurons.

The formation and remodeling of mossy fiber-CA3 pyramidal cell synapses in the stratum lucidum of the hippocampus are implicated in the cellular basis of learning and memory. Afadin and its binding cell adhesion molecules, nectin-1 and nectin-3, together with N-cadherin, are concentrated at puncta a...

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Bibliographic Details
Main Authors: Daisaku Toyoshima, Kenji Mandai, Tomohiko Maruo, Irwan Supriyanto, Hideru Togashi, Takahito Inoue, Masahiro Mori, Yoshimi Takai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3937348?pdf=render

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http://europepmc.org/articles/PMC3937348?pdf=render

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