The mood stabilizing properties of AF3581, a novel potent GSK-3β inhibitor

The mood stabilizing properties of AF3581, a novel potent GSK-3β inhibitor

Glycogen synthase kinase 3β (GSK-3β) is a serine/threonine protein kinase mediating phosphorylation on serine and threonine amino acid residues of several target molecules. The enzyme is involved in the regulation of many cellular processes and aberrant activity of GSK-3β has been linked to several...

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Bibliographic Details
Main Authors: Valeria Capurro, Massimiliano Lanfranco, Maria Summa, Pier Francesca Porceddu, Mariasole Ciampoli, Natasha Margaroli, Lucia Durando, Beatrice Garrone, Rosella Ombrato, Serena Tongiani, Angelo Reggiani
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Bipolar disorders
Depression
GSK3beta
Drug Discovery
Neuropharmacology
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220304418

Internet

http://www.sciencedirect.com/science/article/pii/S0753332220304418

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