Modulation of NKG2D, KIR2DL and Cytokine Production by Pleurotus ostreatus Glucan Enhances Natural Killer Cell Cytotoxicity Toward Cancer Cells

Modulation of NKG2D, KIR2DL and Cytokine Production by Pleurotus ostreatus Glucan Enhances Natural Killer Cell Cytotoxicity Toward Cancer Cells

Medicinal mushrooms have been used for centuries against cancer and infectious diseases. These positive biological effects of mushrooms are due in part to the indirect action of stimulating immune cells. The objective of the current study is to investigate the possible immunomodulatory effects of mu...

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Bibliographic Details
Main Authors: Nehal M. EL-Deeb, Hala I. EL-Adawi, Abeer E. Abd EL-wahab, Ahmed M. Haddad, Hesham A. EL Enshasy, You-Wen He, Keith R. Davis
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
NK cells
mushroom
Pleurotus ostreatus
breast cancer
lung cancer
polysaccharides
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2019.00165/full

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