Estimation of vitamin C human protective dose for acetaminophen toxicity, using acute animal toxicity study

Estimation of vitamin C human protective dose for acetaminophen toxicity, using acute animal toxicity study

Acetaminophen (APAP) is the main cause of fulminant hepatic failure. Vitamin C is a natural antioxidant with protective potentials against APAP toxic damage. In this animal study, and after an LD50 determination and selection of suitable lethal dose, the investigation was done to select a proper pro...

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Bibliographic Details
Main Authors: Mudhaffar I. Al-Farras, Khalid K. Abdul-Razzak, Mohammed Yacoub, Wael M. Hananeh
Format: Article
Language:English
Published: Sulaimani Polytechnic University 2017-07-01
Series:Kurdistan Journal of Applied Research
Subjects:
Acetaminophen, Vitamin C, liver, protective dose, in vivo study
Online Access:http://kjar.spu.edu.iq/index.php/kjar/article/view/56

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