Role of inflammation in depression and anxiety: Tests for disorder specificity, linearity and potential causality of association in the UK Biobank

Role of inflammation in depression and anxiety: Tests for disorder specificity, linearity and potential causality of association in the UK Biobank

Background: Concentrations of C-reactive protein (CRP), interleukin 6 (IL-6) and other inflammatory markers are elevated in people with depression and anxiety compared to controls, but evidence for disorder-specificity, linearity and potential causality is sparse. Methods: Using population-based dat...

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Bibliographic Details
Main Authors: Zheng Ye, Nils Kappelmann, Sylvain Moser, George Davey Smith, Stephen Burgess, Peter B. Jones, Golam M. Khandaker
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:EClinicalMedicine
Subjects:
Depression
Anxiety
Inflammation
CRP
Il-6
Mendelian randomisation
Online Access:http://www.sciencedirect.com/science/article/pii/S2589537021002728

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http://www.sciencedirect.com/science/article/pii/S2589537021002728

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