A Novel High Throughput, Parallel Infection Assay for Determining the Replication Capacities of 346 Primary HIV-1 Isolates of the Zurich Primary HIV-1 Infection Study in Primary Cells

A Novel High Throughput, Parallel Infection Assay for Determining the Replication Capacities of 346 Primary HIV-1 Isolates of the Zurich Primary HIV-1 Infection Study in Primary Cells

HIV-1 replication capacity is an important characteristic to understand the replication competence of single variants or virus populations. It can further aid in the understanding of HIV-1 pathogenicity, disease progression, and drug resistance mutations. To effectively study RC, many assays have be...

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Bibliographic Details
Main Authors: Audrey E. Rindler, Herbert Kuster, Kathrin Neumann, Christine Leemann, Dominique L. Braun, Karin J. Metzner, Huldrych F. Günthard
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Viruses
Subjects:
HIV-1
replication capacity
primary cells
high throughput
parallel infection
primary HIV-1 isolates
Online Access:https://www.mdpi.com/1999-4915/13/3/404

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