Compensatory role of C3 convertase on the strain difference for C3 protein expression in FVB/N, C3H/HeN and C57BL/6N mice

Compensatory role of C3 convertase on the strain difference for C3 protein expression in FVB/N, C3H/HeN and C57BL/6N mice

Abstract To investigate the role of complement C3 (C3) convertase on the strain difference for C3 protein expression in three inbred mice strains, we compared the levels of C2, C3 and C4 mRNA, as well as C3 protein and C3 convertase activity in the serum and liver tissue of FVB/N, C3H/HeN and C57BL/...

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Bibliographic Details
Main Authors: Ji Won Park, Ji Eun Kim, Mi Ju Kang, Hyeon Jun Choi, Su Ji Bae, Dae Youn Hwang
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Laboratory Animal Research
Subjects:
C3H/HeN
C57BL/6N
Complement C3
Convertase activity
FVB/N
Online Access:http://link.springer.com/article/10.1186/s42826-020-0036-7

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