Nuclear Receptor Nur77 Deficiency Alters Dendritic Cell Function

Nuclear Receptor Nur77 Deficiency Alters Dendritic Cell Function

Dendritic cells (DCs) are the professional antigen-presenting cells of the immune system. Proper function of DCs is crucial to elicit an effective immune response against pathogens and to induce antitumor immunity. Different members of the nuclear receptor (NR) family of transcription factors have b...

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Bibliographic Details
Main Authors: Nina Tel-Karthaus, Esther D. Kers-Rebel, Maaike W. Looman, Hiroshi Ichinose, Carlie J. de Vries, Marleen Ansems
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Immunology
Subjects:
dendritic cells
dendritic cell-based immunotherapy
nuclear receptors
NR4A
Nur77
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01797/full

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