The Metamorphic Nature of the Tau Protein: Dynamic Flexibility Comes at a Cost
Accumulation of the microtubule associated protein tau occurs in several neurodegenerative diseases including Alzheimer’s disease (AD). The tau protein is intrinsically disordered, giving it unique structural properties that can be dynamically altered by post-translational modifications such as phos...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2016-01-01
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| Series: | Frontiers in Neuroscience |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00003/full |