Single-cell characterization of in vitro migration and interaction dynamics of T cells expanded with IL-2 and IL-7

Single-cell characterization of in vitro migration and interaction dynamics of T cells expanded with IL-2 and IL-7

T cells are pivotal in the immune defense against cancers and infectious agents. To mount an effector response against cancer cells, T cells need to migrate to the cancer-site, engage in contacts with cancer cells and perform their effector functions. Adoptive T cell therapy is an effective strategy...

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Bibliographic Details
Main Authors: Johanna Maria Tauriainen, Karin eGustafsson, Mårten eGöthlin, Jens eGertow, Marcus eBuggert, Thomas Wilhelm Frisk, Annika C Karlsson, Michael eUhlin, Björn eÖnfelt
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-04-01
Series:Frontiers in Immunology
Subjects:
Microscopy, Fluorescence
Single-Cell Analysis
T cell
IL-2
IL-7
live-cell imaging
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00196/full

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