Spindle cell carcinoma in the maxilla: A rare case and literature review

• Main Authors: M Varshini, Varsha Salian, Pushparaja Shetty, Shalini Krishnan
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2019-01-01
• Series: Dental Research Journal
• Subjects: Maxillary bone; spindle cell carcinoma; squamous cell carcinoma
• Online Access: http://www.drjjournal.net/article.asp?issn=1735-3327;year=2019;volume=16;issue=1;spage=60;epage=63;aulast=Varshini

In India, oral squamous cell carcinoma accounts for 90%–95% of oral malignancies. The WHO classifies spindle cell carcinoma (SpCC) under malignant epithelial tumors of squamous cell carcinoma (SCC) and is a rare entity accounting for only 1% of SCCs. It is an aggressive biphasic neoplasm exhibiting high mortality rate owing to increased metastasis and recurrence which signifies the need for recognition and treatment of this perplexed tumor. We present a case of maxillary SpCC where histopathological evaluation alone was indecisive, requiring immunohistochemistry for confirmation of the diagnosis.