Insulin Resistance in Patients With Acromegaly

Insulin Resistance in Patients With Acromegaly

Acromegaly is characterized by chronic overproduction of growth hormone (GH) that leads to insulin resistance, glucose intolerance and, ultimately, diabetes. The GH-induced sustained stimulation of lipolysis plays a major role not only in the development of insulin resistance and prediabetes/diabete...

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Bibliographic Details
Main Authors: Greisa Vila, Jens Otto L. Jørgensen, Anton Luger, Günter K. Stalla
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Endocrinology
Subjects:
glucose
insulin
growth hormone
IGF-I
acromegaly complications
diabetes
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2019.00509/full

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