Hidradenitis suppurativa: Inside and out

• Main Authors: Sharmila Patil, Astuty Apurwa, Nitin Nadkarni, Shweta Agarwal, Parag Chaudhari, Manjyot Gautam
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2018-01-01
• Series: Indian Journal of Dermatology
• Subjects: Acne inversa; acne triad; adalimumab; Tapocrine gland; hidradenitis suppurativa; Hurley's staging; metformin; Sartorius system
• Online Access: http://www.e-ijd.org/article.asp?issn=0019-5154;year=2018;volume=63;issue=2;spage=91;epage=98;aulast=Patil

Hidradenitis suppurativa is a chronic, disabling, suppurative disease characterized by deep tender subcutaneous nodules; complicated by fibrosis and extensive sinuses affecting primarily the apocrine gland bearing areas. It affects all races in early 20s with greater prevalence seen in women (3 to 5:1). The estimated disease prevalence is 1 - 4 %. The disease is speculated to be caused by follicular structural abnormalities with associated risk factors as smoking, obesity, positive family history and shaving. Certain co-morbidities can also be seen such as inflammatory bowel disease, spondyloarthropathies, epithelial tumors, pyoderma gangrenosum etc. Treatment modalities include counseling of the patient to lose weight if obese, to wear loose clothes, stop smoking and maintain good hygiene. Topical antibiotics, like 1% clindamycin, have shown to give good results along with benzoyl peroxide wash. Orally cocktail of antibiotics can be given, though biologicals remain the best treatment option. Surgical excision can be done in later stages and in recalcitrant cases.