Immunological Aspects of Dental Implant Rejection

Immunological Aspects of Dental Implant Rejection

Nowadays, dental implants are a prominent therapeutic approach among dentists for replacing missing teeth. Failure in dental implants is a severe challenge recently. The factors which lead to dental implant failure are known. These factors can be categorized into different groups. In this article, w...

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Main Authors: Milad Baseri, Faraz Radmand, Reyhaneh Hamedi, Mehdi Yousefi, Hossein Samadi Kafil
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2020/7279509
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spelling doaj-3cf92b6f8ce142e1a652ccec4d736fec2020-12-21T11:41:25ZengHindawi LimitedBioMed Research International2314-61332314-61412020-01-01202010.1155/2020/72795097279509Immunological Aspects of Dental Implant RejectionMilad Baseri0Faraz Radmand1Reyhaneh Hamedi2Mehdi Yousefi3Hossein Samadi Kafil4Dental and Periodontal Research Center, Tabriz University of Medical Sciences, Tabriz, IranBiotechnology Research Center, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, IranDental School, Tabriz University of Medical Sciences, Tabriz, IranResearch Center for Pharmaceutical Nanotechnology, Tabriz University of Medical Sciences, Tabriz, IranDrug Applied Research Center, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, IranNowadays, dental implants are a prominent therapeutic approach among dentists for replacing missing teeth. Failure in dental implants is a severe challenge recently. The factors which lead to dental implant failure are known. These factors can be categorized into different groups. In this article, we discussed the immunological aspects of implant failure as one of these groups. Cytokines and immune cells have extensive and various functions in peri-implantitis. The equilibrium between pro and anti-inflammatory cytokines and cells, which involve in this orchestra, has a crucial role in implant prognosis. In conclusion, immune cells, especially macrophages and dendritic cells, almost increased in the patients with implant failure. Also, proinflammatory cytokines were proposed as diagnostic factors according to their higher levels in dental implant rejection.http://dx.doi.org/10.1155/2020/7279509
collection DOAJ
language English
format Article
sources DOAJ
author Milad Baseri
Faraz Radmand
Reyhaneh Hamedi
Mehdi Yousefi
Hossein Samadi Kafil
spellingShingle Milad Baseri
Faraz Radmand
Reyhaneh Hamedi
Mehdi Yousefi
Hossein Samadi Kafil
Immunological Aspects of Dental Implant Rejection
BioMed Research International
author_facet Milad Baseri
Faraz Radmand
Reyhaneh Hamedi
Mehdi Yousefi
Hossein Samadi Kafil
author_sort Milad Baseri
title Immunological Aspects of Dental Implant Rejection
title_short Immunological Aspects of Dental Implant Rejection
title_full Immunological Aspects of Dental Implant Rejection
title_fullStr Immunological Aspects of Dental Implant Rejection
title_full_unstemmed Immunological Aspects of Dental Implant Rejection
title_sort immunological aspects of dental implant rejection
publisher Hindawi Limited
series BioMed Research International
issn 2314-6133
2314-6141
publishDate 2020-01-01
description Nowadays, dental implants are a prominent therapeutic approach among dentists for replacing missing teeth. Failure in dental implants is a severe challenge recently. The factors which lead to dental implant failure are known. These factors can be categorized into different groups. In this article, we discussed the immunological aspects of implant failure as one of these groups. Cytokines and immune cells have extensive and various functions in peri-implantitis. The equilibrium between pro and anti-inflammatory cytokines and cells, which involve in this orchestra, has a crucial role in implant prognosis. In conclusion, immune cells, especially macrophages and dendritic cells, almost increased in the patients with implant failure. Also, proinflammatory cytokines were proposed as diagnostic factors according to their higher levels in dental implant rejection.
url http://dx.doi.org/10.1155/2020/7279509
work_keys_str_mv AT miladbaseri immunologicalaspectsofdentalimplantrejection
AT farazradmand immunologicalaspectsofdentalimplantrejection
AT reyhanehhamedi immunologicalaspectsofdentalimplantrejection
AT mehdiyousefi immunologicalaspectsofdentalimplantrejection
AT hosseinsamadikafil immunologicalaspectsofdentalimplantrejection
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