An Endostatin-lentivirus (ES-LV)-EPC gene therapy agent for suppression of neovascularization in oxygen-induced retinopathy rat model

An Endostatin-lentivirus (ES-LV)-EPC gene therapy agent for suppression of neovascularization in oxygen-induced retinopathy rat model

Abstract Background Transplantation of gene transfected endothelial progenitor cells (EPCs) has provided novel methods for tumor neovascularization therapy but not for ocular disease therapy. This study aimed to investigate the efficacy of endostatin transfected EPCs in retinal neovascularization th...

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Bibliographic Details
Main Authors: Jing Ai, Jian Ma, Zhi-Qing Chen, Jun-Hui Sun, Ke Yao
Format: Article
Language:English
Published: BMC 2020-07-01
Series:BMC Molecular and Cell Biology
Subjects:
Retinal neovascularization
Endothelial progenitor cells
Gene therapy
Endostatin
Online Access:http://link.springer.com/article/10.1186/s12860-020-00301-1

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