The MAO Inhibitor Tranylcypromine Alters LPS- and Aβ-Mediated Neuroinflammatory Responses in Wild-type Mice and a Mouse Model of AD

Monoamine oxidase (MAO) has been implicated in neuroinflammation, and therapies targeting MAO are of interest for neurodegenerative diseases. The small-molecule drug tranylcypromine, an inhibitor of MAO, is currently used as an antidepressant and in the treatment of cancer. However, whether tranylcy...

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Bibliographic Details
Main Authors: HyunHee Park, Kyung-Min Han, Hyongjun Jeon, Ji-Soo Lee, Hyunju Lee, Seong Gak Jeon, Jin-Hee Park, Yu Gyung Kim, Yuxi Lin, Young-Ho Lee, Yun Ha Jeong, Hyang-Sook Hoe
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Cells
Subjects:
LPS
Online Access:https://www.mdpi.com/2073-4409/9/9/1982