Expression profiling in APP23 mouse brain: inhibition of Aβ amyloidosis and inflammation in response to LXR agonist treatment

<p>Abstract</p> <p>Background</p> <p>Recent studies demonstrate that in addition to its modulatory effect on APP processing, <it>in vivo </it>application of Liver X Receptor agonist T0901317 (T0) to APP transgenic and non-transgenic mice decreases the level...

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Bibliographic Details
Main Authors: Mangelsdorf David, Staufenbiel Matthias, Wang Zhu, Bookout Angie, Lefterov Iliya, Koldamova Radosveta
Format: Article
Language:English
Published: BMC 2007-10-01
Series:Molecular Neurodegeneration
Online Access:http://www.molecularneurodegeneration.com/content/2/1/20