Revisiting the "satisfaction of spatial restraints" approach of MODELLER for protein homology modeling.

The most frequently used approach for protein structure prediction is currently homology modeling. The 3D model building phase of this methodology is critical for obtaining an accurate and biologically useful prediction. The most widely employed tool to perform this task is MODELLER. This program im...

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Bibliographic Details
Main Authors: Giacomo Janson, Alessandro Grottesi, Marco Pietrosanto, Gabriele Ausiello, Giulia Guarguaglini, Alessandro Paiardini
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-12-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1007219