MFI-Net: A multi-resolution fusion input network for retinal vessel segmentation.

Segmentation of retinal vessels is important for doctors to diagnose some diseases. The segmentation accuracy of retinal vessels can be effectively improved by using deep learning methods. However, most of the existing methods are incomplete for shallow feature extraction, and some superficial featu...

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Main Authors: Yun Jiang, Chao Wu, Ge Wang, Hui-Xia Yao, Wen-Huan Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0253056
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spelling doaj-3ce867d7eca64fdb94012dbc73d4a8852021-07-30T04:30:24ZengPublic Library of Science (PLoS)PLoS ONE1932-62032021-01-01167e025305610.1371/journal.pone.0253056MFI-Net: A multi-resolution fusion input network for retinal vessel segmentation.Yun JiangChao WuGe WangHui-Xia YaoWen-Huan LiuSegmentation of retinal vessels is important for doctors to diagnose some diseases. The segmentation accuracy of retinal vessels can be effectively improved by using deep learning methods. However, most of the existing methods are incomplete for shallow feature extraction, and some superficial features are lost, resulting in blurred vessel boundaries and inaccurate segmentation of capillaries in the segmentation results. At the same time, the "layer-by-layer" information fusion between encoder and decoder makes the feature information extracted from the shallow layer of the network cannot be smoothly transferred to the deep layer of the network, resulting in noise in the segmentation features. In this paper, we propose the MFI-Net (Multi-resolution fusion input network) network model to alleviate the above problem to a certain extent. The multi-resolution input module in MFI-Net avoids the loss of coarse-grained feature information in the shallow layer by extracting local and global feature information in different resolutions. We have reconsidered the information fusion method between the encoder and the decoder, and used the information aggregation method to alleviate the information isolation between the shallow and deep layers of the network. MFI-Net is verified on three datasets, DRIVE, CHASE_DB1 and STARE. The experimental results show that our network is at a high level in several metrics, with F1 higher than U-Net by 2.42%, 2.46% and 1.61%, higher than R2U-Net by 1.47%, 2.22% and 0.08%, respectively. Finally, this paper proves the robustness of MFI-Net through experiments and discussions on the stability and generalization ability of MFI-Net.https://doi.org/10.1371/journal.pone.0253056
collection DOAJ
language English
format Article
sources DOAJ
author Yun Jiang
Chao Wu
Ge Wang
Hui-Xia Yao
Wen-Huan Liu
spellingShingle Yun Jiang
Chao Wu
Ge Wang
Hui-Xia Yao
Wen-Huan Liu
MFI-Net: A multi-resolution fusion input network for retinal vessel segmentation.
PLoS ONE
author_facet Yun Jiang
Chao Wu
Ge Wang
Hui-Xia Yao
Wen-Huan Liu
author_sort Yun Jiang
title MFI-Net: A multi-resolution fusion input network for retinal vessel segmentation.
title_short MFI-Net: A multi-resolution fusion input network for retinal vessel segmentation.
title_full MFI-Net: A multi-resolution fusion input network for retinal vessel segmentation.
title_fullStr MFI-Net: A multi-resolution fusion input network for retinal vessel segmentation.
title_full_unstemmed MFI-Net: A multi-resolution fusion input network for retinal vessel segmentation.
title_sort mfi-net: a multi-resolution fusion input network for retinal vessel segmentation.
publisher Public Library of Science (PLoS)
series PLoS ONE
issn 1932-6203
publishDate 2021-01-01
description Segmentation of retinal vessels is important for doctors to diagnose some diseases. The segmentation accuracy of retinal vessels can be effectively improved by using deep learning methods. However, most of the existing methods are incomplete for shallow feature extraction, and some superficial features are lost, resulting in blurred vessel boundaries and inaccurate segmentation of capillaries in the segmentation results. At the same time, the "layer-by-layer" information fusion between encoder and decoder makes the feature information extracted from the shallow layer of the network cannot be smoothly transferred to the deep layer of the network, resulting in noise in the segmentation features. In this paper, we propose the MFI-Net (Multi-resolution fusion input network) network model to alleviate the above problem to a certain extent. The multi-resolution input module in MFI-Net avoids the loss of coarse-grained feature information in the shallow layer by extracting local and global feature information in different resolutions. We have reconsidered the information fusion method between the encoder and the decoder, and used the information aggregation method to alleviate the information isolation between the shallow and deep layers of the network. MFI-Net is verified on three datasets, DRIVE, CHASE_DB1 and STARE. The experimental results show that our network is at a high level in several metrics, with F1 higher than U-Net by 2.42%, 2.46% and 1.61%, higher than R2U-Net by 1.47%, 2.22% and 0.08%, respectively. Finally, this paper proves the robustness of MFI-Net through experiments and discussions on the stability and generalization ability of MFI-Net.
url https://doi.org/10.1371/journal.pone.0253056
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