Ultra-high resolution optical coherence tomography analysis of bull's eye maculopathy in chloroquine users

• Main Authors: Celso Morita, Daniel Araujo Ferraz, Thais Zamudio Igami, Beatriz Sayuri Takahashi, Tiago Faria e Arantes, Walter Yukihiko Takahashi
• Format: Article
• Language: English
• Published: Sociedade Brasileira de Oftalmologia 2014-06-01
• Series: Revista Brasileira de Oftalmologia
• Subjects: Cloroquina/toxicidade; Tomografia de coerência óptica/instrumentação; Tomografia de coerência óptica/tendências; Tomografia de coerência óptica/utilização; Retina/efeitos de drogas; Doenças retinianas/dignóstico
• Online Access: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0034-72802014000300135&lng=en&tlng=en

Purpose: Register and compare anatomical changes, structural and quantitative found in optical coherence tomography Stratus and Topcon 3D in chronic users of chloroquine. Methods: Five patients were diagnosed with toxic "bull's eye" maculopathy was submitted to macular optical coherence tomography examination (Stratus and Topcon 3D). Results: Both tools demonstrated an increase reflectivity of choriocapillaris unit just foveal retinal pigment epithelium atrophy. However, Topcon 3D provided to all patients better description of the line corresponding to the transition between inner and outer segments of photoreceptors. Using the possibility of assembling threedimensional images and subtraction selective retinal layers, we found a lesion with a target that reflects the greater thickness of retinal pigment epithelium in central and parafoveal region that is matched to preserve macular photoreceptors. Conclusion: it was observed better resolution and faster image capture by Topcon 3D than Stratus OCT, that provided more detailed analysis of the line corresponding to transition between outer and inner segment of photoreceptors in macular region. With Topcon 3D, it was possible to evaluate soundly the thickness of retinal pigment epithelium in central and parafoveal region that caused an increase reflectivity of choriocapillaris creating a image with a target unpublished before.